Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3308Two-component response regulator. (254 aa)    
Predicted Functional Partners:
CBO3309
Two-component sensor kinase.
 
 0.998
CBO3310
Family includes Escherichia coli carbon starvation protein SWALL:CSTA_ECOLI (SWALL:P15078).
 
   
 0.616
CBO0325
Putative membrane protein; Similar to Clostridium tetani murein hydrolase export regulator ctc01826 SWALL:Q893J2 (EMBL:AE015942) (229 aa) fasta scores: E(): 1.6e-59, 72.92 38d in 229 aa.
    
 0.577
CBO0248
Two-component sensor kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 sensor protein DcuS or b4125 or z5727 or ecs5107 SWALL:DCUS_ECOLI (SWALL:P39272) (543 aa) fasta scores: E(): 1.4e-44, 31.09 38d in 537 aa, and to Clostridium tetani sensor kinase DpiB or ctc01524 SWALL:Q894L7 (EMBL:AE015941) (538 aa) fasta scores: E(): 4.2e-67,41.17 38d in 544 aa.
 
  
 0.438
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (24%) [HD]