CBO3349 protein (Clostridium botulinum A ATCC 3502)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CBO3349

Two-component sensor kinase. (461 aa)

Predicted Functional Partners:

CBO3349A

0.958

CBO0365

0.828

CBO0610

0.826

CBO2285

0.822

CBO1613

0.821

CBO0776

0.804

CBO1041

0.804

CBO1926

0.803

CBO1968

0.803

CBO0352

0.802

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
CBO0352	CBO3349	Two-component response regulator; Similar to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP or bsu29110 SWALL:PHOP_BACSU (SWALL:P13792) (240 aa) fasta scores: E(): 1.6e-34, 46.72 38d in 229 aa.	Two-component sensor kinase.	0.802
CBO0365	CBO1968	Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR vanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 2.2e-41, 51.94 38d in 231 aa.	Two-component response regulator.	0.909
CBO0365	CBO3349	Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR vanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 2.2e-41, 51.94 38d in 231 aa.	Two-component sensor kinase.	0.828
CBO0610	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.826
CBO0776	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.804
CBO1041	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.804
CBO1613	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.821
CBO1926	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.803
CBO1968	CBO0365	Two-component response regulator.	Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR vanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 2.2e-41, 51.94 38d in 231 aa.	0.909
CBO1968	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.803
CBO2285	CBO3349	Two-component response regulator.	Two-component sensor kinase.	0.822
CBO3349	CBO0352	Two-component sensor kinase.	Two-component response regulator; Similar to Bacillus subtilis alkaline phosphatase synthesis transcriptional regulatory protein PhoP or bsu29110 SWALL:PHOP_BACSU (SWALL:P13792) (240 aa) fasta scores: E(): 1.6e-34, 46.72 38d in 229 aa.	0.802
CBO3349	CBO0365	Two-component sensor kinase.	Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR vanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 2.2e-41, 51.94 38d in 231 aa.	0.828
CBO3349	CBO0610	Two-component sensor kinase.	Two-component response regulator.	0.826
CBO3349	CBO0776	Two-component sensor kinase.	Two-component response regulator.	0.804
CBO3349	CBO1041	Two-component sensor kinase.	Two-component response regulator.	0.804
CBO3349	CBO1613	Two-component sensor kinase.	Two-component response regulator.	0.821
CBO3349	CBO1926	Two-component sensor kinase.	Two-component response regulator.	0.803
CBO3349	CBO1968	Two-component sensor kinase.	Two-component response regulator.	0.803
CBO3349	CBO2285	Two-component sensor kinase.	Two-component response regulator.	0.822