Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
licAPTS system, lichenan-specific IIa component. (98 aa)    
Predicted Functional Partners:
licB
PTS system, lichenan-specific IIb component.
 
 0.999
licC
PTS system, lichenan-specific IIc component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
 
 0.999
ascB
6-phospho-beta-glucosidase.
 
 
 0.978
CBO1202
6-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.977
licH
6-phospho-beta-glucosidase.
 
 
 0.968
ptsH
Putative phosphocarrier protein HPr.
   
 0.945
CBO3358
Putative transcriptional regulatory protein.
 
   
 0.897
CBO3354
Conserved hypothetical protein.
 
     0.865
fruK
1-phosphofructokinase; This CDS is also similar to CBO1992 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.747
CBO3355
Putative activator of 2-hydroxyacyl-CoA-hydratase.
 
     0.722
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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