Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3364Conserved hypothetical protein. (398 aa)    
Predicted Functional Partners:
CBO0856
Putative acetyltransferase.
  
     0.734
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
     0.685
CBO0750
Putative transposase (partial); Partial CDS. Similar to internal regions of several transposases including Thiobacillus ferrooxidans resolvase-like protein SWALL:O33828 (EMBL:U73041) (859 aa) fasta scores: E(): 4.3e-18, 42.74 38d in 124 aa, and to Streptomyces fradiae transposase for transposon tn4556 tnpA SWALL:TNPA_STRFR (SWALL:P20189) (892 aa) fasta scores: E(): 6.4, 26.44 38d in 121 aa; was marked partial.
  
     0.632
CBO2132
Conserved hypothetical protein.
  
     0.618
CBO2267
Hypothetical protein; Highly similar to CBO1594 (85.5 38d), CBO0900 (85.5 38d) and CBO2273 (82.3 0d).
  
     0.610
CBO1594
Hypothetical protein; No significant database matches; Highly similar to CBO0900 (85.5 38d), CBO2273 (85.5 38d) and CBO2267 (93.7 0d).
  
     0.609
CBO2273
Hypothetical protein; Similar to the N-terminal region of Bacillus subtilis hypothetical protein YmaF or bsu17320 SWALL:YMAF_BACSU (SWALL:O31794) (137 aa) fasta scores: E(): 0.0051, 30.3 38d in 99 aa; Highly similar to CBO0900 (82.3 38d), CBO1594 (85.5 38d) and CBO12267 (89.9 0d).
  
     0.609
CBO0900
Hypothetical protein; No significant database matches; Highly similar to CBO1594 (85.5 38d), CBO2273 (82.3 38d) and CBO2267 (85.5 0d).
  
     0.601
chiD
Chitinase.
  
     0.564
CBO0620
TetR-family transcriptional regulator.
  
     0.562
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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