Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3367Conserved hypothetical protein. (284 aa)    
Predicted Functional Partners:
hymB
Putative electron-transferring subunit of iron-only hydrogenase.
  
 0.998
CBO1505
Putative oxidoreductase.
 
 
 0.938
CBO1829
Conserved hypothetical protein; Similar to the C-terminal region of several oxidoreductases such as Eubacterium acidaminophilum HymA protein.
   
 0.899
hymA
Putative electron-transferring subunit of iron-only hydrogenase.
   
 0.899
CBO2587
Putative AMP-binding enzyme; Similar to an internal region of Bacillus licheniformis bacitracin synthetase 1 BacA SWALL:BACA_BACLI (SWALL:O68006) (5255 aa) fasta scores: E(): 4.3e-49, 33.15 38d in 561 aa.
  
 0.860
CBO2187
Putative exported protein; C-terminus is similar to the C-terminal region of Escherichia coli acetyl esterase Aes or b0476 SWALL:AES_ECOLI (SWALL:P23872) (319 aa) fasta scores: E(): 9.8e-14, 26.78 38d in 280 aa.
 
 
 0.856
CBO0482
Similar to Bacillus halodurans hypothetical protein Bh1562 SWALL:Q9KCK9 (EMBL:AP001512) (268 aa) fasta scores: E(): 4.7e-46, 45.14 38d in 268 aa.
   
 
 0.813
fesA
Putative ferredoxin.
  
 0.808
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
  
 0.801
CBO0010
Conserved hypothetical protein; Similar to Methanobacterium thermoautotrophicum hypothetical protein Mth772 SWALL:O26866 (EMBL:AE000856) (375 aa) fasta scores: E(): 2.1e-24, 31.88 38d in 345 aa,and to Methanosarcina mazei iron-sulfur cluster-binding protein mm0611 SWALL:Q8PZ83 (EMBL:AE013286) (376 aa) fasta scores: E(): 7.6e-22, 31.37 38d in 357 aa.
   
 0.795
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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