STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tkt-2Transketolase, thiamine disphosphate-bindin subunit; Similar to the N-terminal region of several transketolase including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 3.8e-36, 42.85 38d in 273 aa. (274 aa)    
Predicted Functional Partners:
tkt
Transketolase, pyridine binding subunit; Similar to C-terminal region of several transketolases including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 6e-37, 40.69 38d in 317 aa.
 0.999
rpe
Putative ribulose-phosphate 3-epimerase; Similar to the C-terminal region of Solanum tuberosum ribulose-phosphate 3-epimerase, chloroplast precursor SWALL:RPE_SOLTU (SWALL:Q43843) (280 aa) fasta scores: E(): 1.7e-34, 51.4 38d in 214 aa.
 
 0.995
glpX
Putative fructose-1,6-bisphosphatase class II GlpX.
 
   
  0.954
tal
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
 
  
 0.928
CBO2153
Putative transaldolase.
 
  
 0.928
rpiB
Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB or b4090 SWALL:RPIB_ECOLI (SWALL:P37351) (149 aa) fasta scores: E(): 2.2e-27, 52.77 38d in 144 aa,and to Clostridium tetani ribose 5-phosphate isomerase ctc00307 SWALL:Q898Y0 (EMBL:AE015936) (149 aa) fasta scores: E(): 1.5e-43, 78.47 38d in 144 aa.
  
 
 0.918
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
     
 0.910
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.910
fba
Similar to Entamoeba histolytica putative fructose-1,6-bisphosphate aldolase Ald SWALL:Q8MTW2 (EMBL:AY057996) (326 aa) fasta scores: E(): 5.8e-51, 49.2 id in 315 aa, and to Clostridium tetani fructose-bisphosphate aldolase ctc00341 SWALL:Q898U8 (EMBL:AE015937) (320 aa) fasta scores: E(): 3.3e-80,76.75 38d in 314 aa.
    
 0.906
deoC
Putative deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.906
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.