Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
alr-2Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (386 aa)    
Predicted Functional Partners:
ddlB
D-alanine--d-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.942
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.939
Alr
Alanine racemase; Similar to Treponema pallidum alanine racemase Alr or tp0681 SWALL:ALR_TREPA (SWALL:Q56346) (377 aa) fasta scores: E(): 9.7e-37, 35.93 38d in 384 aa, and to Clostridium acetobutylicum alanine racemase 1 Alr1 or cac0492 SWALL:ALR1_CLOAB (SWALL:Q97LR2) (386 aa) fasta scores: E(): 8e-87, 58.98 38d in 395 aa.
  
  
 
0.902
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 
0.902
glnA
Glutamine synthetase.
     
 0.823
gluD
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.808
asdA
L-aspartate beta-decarboxylase.
    
 0.806
gadA
Glutamate decarboxylase alpha; Belongs to the group II decarboxylase family.
    
  0.805
gltD
Glutamate synthase [NADPH] small chain.
     
  0.800
glsA
Glutaminase; Belongs to the glutaminase family.
     
  0.800
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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