yihY protein (Clostridium botulinum A ATCC 3502)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

yihY

Putative membrane-associated ribonuclease; Belongs to the UPF0761 family. (285 aa)

Predicted Functional Partners:

CBO0143

0.664

CBO3402

0.611

nnrE

0.533

cypC

0.495

CBO3404

0.470

CBO1505

0.447

metH

0.407

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBO0143	yihY	CBO0143	CBO3403	Similar to Acinetobacter johnsonii low molecular weight protein-tyrosine-phosphatase Ptp SWALL:PTP_ACIJO (SWALL:O52787) (142 aa) fasta scores: E(): 4.2e-06, 33.59 id in 128 aa, and to Clostridium tetani phosphotyrosine protein phosphatase ctc00306 SWALL:Q898Y1 (EMBL:AE015936) (154 aa) fasta scores: E(): 1.9e-24, 54.05 38d in 148 aa.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.664
CBO1505	cypC	CBO1505	CBO1038	Putative oxidoreductase.	Fatty acid beta-hydroxylating cytochrome P450.	0.538
CBO1505	nnrE	CBO1505	CBO3399	Putative oxidoreductase.	Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]	0.506
CBO1505	yihY	CBO1505	CBO3403	Putative oxidoreductase.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.447
CBO3402	yihY	CBO3402	CBO3403	Putative Na+/H+ antiporter.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.611
CBO3404	yihY	CBO3404	CBO3403	Conserved hypothetical protein.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.470
cypC	CBO1505	CBO1038	CBO1505	Fatty acid beta-hydroxylating cytochrome P450.	Putative oxidoreductase.	0.538
cypC	yihY	CBO1038	CBO3403	Fatty acid beta-hydroxylating cytochrome P450.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.495
metH	yihY	CBO1623	CBO3403	Putative methionine synthase.	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.407
nnrE	CBO1505	CBO3399	CBO1505	Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]	Putative oxidoreductase.	0.506
nnrE	yihY	CBO3399	CBO3403	Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	0.533
yihY	CBO0143	CBO3403	CBO0143	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Similar to Acinetobacter johnsonii low molecular weight protein-tyrosine-phosphatase Ptp SWALL:PTP_ACIJO (SWALL:O52787) (142 aa) fasta scores: E(): 4.2e-06, 33.59 id in 128 aa, and to Clostridium tetani phosphotyrosine protein phosphatase ctc00306 SWALL:Q898Y1 (EMBL:AE015936) (154 aa) fasta scores: E(): 1.9e-24, 54.05 38d in 148 aa.	0.664
yihY	CBO1505	CBO3403	CBO1505	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Putative oxidoreductase.	0.447
yihY	CBO3402	CBO3403	CBO3402	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Putative Na+/H+ antiporter.	0.611
yihY	CBO3404	CBO3403	CBO3404	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Conserved hypothetical protein.	0.470
yihY	cypC	CBO3403	CBO1038	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Fatty acid beta-hydroxylating cytochrome P450.	0.495
yihY	metH	CBO3403	CBO1623	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Putative methionine synthase.	0.407
yihY	nnrE	CBO3403	CBO3399	Putative membrane-associated ribonuclease; Belongs to the UPF0761 family.	Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]	0.533