Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
buk1Butyrate kinase 1; Also similar to CBO3428 (57.670 38d. in 352 aa overlap); Belongs to the acetokinase family. (356 aa)    
Predicted Functional Partners:
ptb2
Phosphate butyryltransferase; Also similar to CBO3118 (53.37 38d).
 
 0.999
ptb1
Phosphate butyryltransferase; Also similar to CBO3427 (53.37 38d).
 
 0.994
buk2
Butyrate kinase 2; Also similar to CBO3426 (57.670 38d. in 352 aa overlap); Belongs to the acetokinase family.
 
  
 
0.975
ctfA
Butyrate-acetoacetate CoA-transferase subunit A.
     
 0.939
ctfB
Butyrate-acetoacetate CoA-transferase subunit B.
     
 0.937
ptA
Phosphate acetyltransferase.
 
  
 0.921
thl
acetyl-CoA acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.806
hbd
3-hydroxybutyryl-CoA dehydrogenase.
     
 0.800
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
     
 0.678
gluD
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.677
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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