Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxB3Thioredoxin reductase. (287 aa)    
Predicted Functional Partners:
trxC
Thioredoxin; Belongs to the thioredoxin family.
 
 0.977
trxB1
Thioredoxin reductase.
  
  
 
0.919
trxB2
Thioredoxin reductase.
  
  
 
0.916
selD
Selenide,water dikinase 1; Synthesizes selenophosphate from selenide and ATP.
     
 0.907
ygfK
Pyridine nucleotide-disulfide oxidoreductase.
  
 
 0.906
mdeA
Similar to Pseudomonas putida methionine gamma-lyase MdeA SWALL:MEGL_PSEPU (SWALL:P13254) (398 aa) fasta scores: E(): 3e-82, 53.03 38d in 396 aa, and to Clostridium tetani cys/met metabolism lyase ctc02530 SWALL:Q890V5 (EMBL:AE015944) (398 aa) fasta scores: E(): 3.2e-115, 73.61 38d in 398 aa.
   
 
 0.904
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.839
CBO2765
Conserved hypothetical protein.
  
 
 0.597
acdB
acyl-CoA dehydrogenase, short-chain specific.
      
 0.594
CBO1006
Conserved hypothetical protein.
      
 0.593
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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