STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)    
Predicted Functional Partners:
cysE
Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.
 
  
 0.983
mrnC
Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
  
 0.962
yacO
Putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
 
 0.933
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
 
  
 0.892
CBO3498
Conserved hypothetical protein.
  
  
 0.880
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
     
 0.843
queD
Putative 6-pyruvoyl tetrahydrobiopterin synthase.
  
  
 0.825
queD-2
Conserved hypothetical protein.
  
  
 0.825
leuS
Similar to Escherichia coli leucyl-tRNA synthetase LeuS or b0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 4.7e-104, 40.67 38d in 858 aa, and to Clostridium tetani leucyl-tRNA synthetase LeuSor ctc00337 SWALL:SYL_CLOTE (SWALL:Q898V2) (812 aa) fasta scores: E(): 0, 76.26 38d in 813 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.819
hisS
histidyl-tRNA synthetase.
  
 
 0.813
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.