| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBO2233 | glyA | CBO2233 | CBO2595 | Putative threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| CBO2233 | tdcB | CBO2233 | CBO3502 | Putative threonine aldolase. | Threonine dehydratase catabolic. | 0.976 |
| CBO2233 | thrC | CBO2233 | CBO1638 | Putative threonine aldolase. | Threonine synthase. | 0.927 |
| CBO2756 | metH | CBO2756 | CBO1623 | Putative aminotransferase; Possible alternative translational start site. | Putative methionine synthase. | 0.653 |
| CBO2756 | tdcB | CBO2756 | CBO3502 | Putative aminotransferase; Possible alternative translational start site. | Threonine dehydratase catabolic. | 0.890 |
| CBO2756 | thrC | CBO2756 | CBO1638 | Putative aminotransferase; Possible alternative translational start site. | Threonine synthase. | 0.495 |
| cysD | metC | CBO1876 | CBO0726 | O-acetylhomoserine sulfhydrylase. | Cystathionine beta-lyase. | 0.935 |
| cysD | metH | CBO1876 | CBO1623 | O-acetylhomoserine sulfhydrylase. | Putative methionine synthase. | 0.975 |
| cysD | tdcB | CBO1876 | CBO3502 | O-acetylhomoserine sulfhydrylase. | Threonine dehydratase catabolic. | 0.851 |
| glyA | CBO2233 | CBO2595 | CBO2233 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative threonine aldolase. | 0.939 |
| glyA | metH | CBO2595 | CBO1623 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative methionine synthase. | 0.955 |
| glyA | pssA | CBO2595 | CBO0198 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Similar to Bacillus subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or bsu02270 SWALL:PSS_BACSU (SWALL:P39823) (177 aa) fasta scores: E(): 5.7e-17, 39.15 38d in 166 aa, and to Clostridium tetani CDP-diacylglycerol--serine O-phosphatidyltransferase ctc00346 SWALL:Q898U4 (EMBL:AE015937) (175 aa) fasta scores: E(): 3.4e-45,70.17 38d in 171 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | sdhA | CBO2595 | CBO1215 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.960 |
| glyA | sdhB | CBO2595 | CBO1214 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.962 |
| glyA | tdcB | CBO2595 | CBO3502 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase catabolic. | 0.924 |
| metC | cysD | CBO0726 | CBO1876 | Cystathionine beta-lyase. | O-acetylhomoserine sulfhydrylase. | 0.935 |
| metC | metH | CBO0726 | CBO1623 | Cystathionine beta-lyase. | Putative methionine synthase. | 0.978 |
| metC | tdcB | CBO0726 | CBO3502 | Cystathionine beta-lyase. | Threonine dehydratase catabolic. | 0.834 |
| metH | CBO2756 | CBO1623 | CBO2756 | Putative methionine synthase. | Putative aminotransferase; Possible alternative translational start site. | 0.653 |
| metH | cysD | CBO1623 | CBO1876 | Putative methionine synthase. | O-acetylhomoserine sulfhydrylase. | 0.975 |