tdcB protein (Clostridium botulinum A ATCC 3502)

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Score

tdcB

Threonine dehydratase catabolic. (407 aa)

Predicted Functional Partners:

CBO2233

0.969

glyA

0.967

thrC

0.939

sdhB

0.925

sdhA

0.922

pssA

0.901

CBO2756

0.896

metH

0.890

cysE

0.838

ldh

0.834

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBO2233	glyA	CBO2233	CBO2595	Putative threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.941
CBO2233	tdcB	CBO2233	CBO3502	Putative threonine aldolase.	Threonine dehydratase catabolic.	0.969
CBO2233	thrC	CBO2233	CBO1638	Putative threonine aldolase.	Threonine synthase.	0.933
CBO2756	ldh	CBO2756	CBO1519	Putative aminotransferase; Possible alternative translational start site.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.	0.852
CBO2756	metH	CBO2756	CBO1623	Putative aminotransferase; Possible alternative translational start site.	Putative methionine synthase.	0.675
CBO2756	tdcB	CBO2756	CBO3502	Putative aminotransferase; Possible alternative translational start site.	Threonine dehydratase catabolic.	0.896
CBO2756	thrC	CBO2756	CBO1638	Putative aminotransferase; Possible alternative translational start site.	Threonine synthase.	0.488
cysE	glyA	CBO0206	CBO2595	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.864
cysE	pssA	CBO0206	CBO0198	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	Similar to Bacillus subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or bsu02270 SWALL:PSS_BACSU (SWALL:P39823) (177 aa) fasta scores: E(): 5.7e-17, 39.15 38d in 166 aa, and to Clostridium tetani CDP-diacylglycerol--serine O-phosphatidyltransferase ctc00346 SWALL:Q898U4 (EMBL:AE015937) (175 aa) fasta scores: E(): 3.4e-45,70.17 38d in 171 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.802
cysE	sdhA	CBO0206	CBO1215	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	Putative L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.909
cysE	sdhB	CBO0206	CBO1214	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	Putative L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.909
cysE	tdcB	CBO0206	CBO3502	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	Threonine dehydratase catabolic.	0.838
glyA	CBO2233	CBO2595	CBO2233	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative threonine aldolase.	0.941
glyA	cysE	CBO2595	CBO0206	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.	0.864
glyA	metH	CBO2595	CBO1623	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative methionine synthase.	0.946
glyA	pssA	CBO2595	CBO0198	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Similar to Bacillus subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or bsu02270 SWALL:PSS_BACSU (SWALL:P39823) (177 aa) fasta scores: E(): 5.7e-17, 39.15 38d in 166 aa, and to Clostridium tetani CDP-diacylglycerol--serine O-phosphatidyltransferase ctc00346 SWALL:Q898U4 (EMBL:AE015937) (175 aa) fasta scores: E(): 3.4e-45,70.17 38d in 171 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.900
glyA	sdhA	CBO2595	CBO1215	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.970
glyA	sdhB	CBO2595	CBO1214	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.970
glyA	tdcB	CBO2595	CBO3502	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Threonine dehydratase catabolic.	0.967
ldh	CBO2756	CBO1519	CBO2756	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.	Putative aminotransferase; Possible alternative translational start site.	0.852