STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdcBThreonine dehydratase catabolic. (407 aa)    
Predicted Functional Partners:
CBO2233
Putative threonine aldolase.
  
 
 0.976
thrC
Threonine synthase.
  
 
 0.952
sdhB
Putative L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.937
sdhA
Putative L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.937
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.924
pssA
Similar to Bacillus subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or bsu02270 SWALL:PSS_BACSU (SWALL:P39823) (177 aa) fasta scores: E(): 5.7e-17, 39.15 38d in 166 aa, and to Clostridium tetani CDP-diacylglycerol--serine O-phosphatidyltransferase ctc00346 SWALL:Q898U4 (EMBL:AE015937) (175 aa) fasta scores: E(): 3.4e-45,70.17 38d in 171 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.900
CBO2756
Putative aminotransferase; Possible alternative translational start site.
  
 
 0.890
metH
Putative methionine synthase.
  
 0.888
cysD
O-acetylhomoserine sulfhydrylase.
   
 
 0.851
metC
Cystathionine beta-lyase.
  
 
 0.834
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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