STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVBStage V sporulation protein B. (511 aa)    
Predicted Functional Partners:
CBO3535
MazG family protein; Similar over its C-terminal region to Escherichia coli, and Escherichia coli O157:H7 MazG protein or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 7.8e-33, 41.96 38d in 255 aa, and similar over its entire length to Clostridium tetani conserved protein ctc00198 SWALL:Q899H9 (EMBL:AE015936) (491 aa) fasta scores: E(): 3.4e-118, 66.18 38d in 482 aa.
  
    0.876
yabQ
Putative membrane protein.
 
  
 0.801
yabP
Conserved hypothetical protein.
  
  
 0.780
spoVT
Stage V sporulation protein T.
 
   
 0.772
hup
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
       0.717
CBO3533
Putative RNA-binding protein.
  
    0.708
CBO2563
Conserved hypothetical protein; Belongs to the UPF0297 family.
  
     0.682
CBO2936
Conserved hypothetical protein.
  
     0.640
sigH
RNA polymerase sigma-H factor; Belongs to the sigma-70 factor family.
  
    0.637
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.637
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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