STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVTStage V sporulation protein T. (183 aa)    
Predicted Functional Partners:
spoIIID
Similar to Bacillus subtilis stage III sporulation protein D SpoIIID or bsu36420 SWALL:SP3D_BACSU (SWALL:P15281) (93 aa) fasta scores: E(): 1.1e-16, 62.65 id in 83 aa, and to Clostridium acetobutylicum stage iii sporulation protein D SpoIIID cac2859 SWALL:Q97F82 (EMBL:AE007783) (84 aa) fasta scores: E(): 9e-24, 89.28 id in 84 aa.
  
  
 0.957
spoIIR
Similar to Bacillus subtilis stage II sporulation protein R SpoIIR or Ipc-27d or bsu36970 SWALL:SP2R_BACSU (SWALL:P39151) (224 aa) fasta scores: E(): 1.9e-18, 35.71 id in 224 aa, and to Clostridium perfringens stage II sporulation protein R SpoIIR or cpe2211 SWALL:Q8XIB0 (EMBL:AP003193) (209 aa) fasta scores: E(): 1.5e-37,55.34 38d in 206 aa.
  
   
 0.919
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.896
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.880
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.855
spoVAD
Stage V sporulation protein AD.
  
   
 0.852
spoIIIAA
Stage III sporulation protein AA.
  
   
 0.851
spoIIIAG
Stage III sporulation protein AG.
  
   
 0.846
spoIIP
Putative stage II sporulation protein P.
  
   
 0.843
spoIIE
Putative stage II sporulation protein.
 
   
 0.840
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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