STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3589Putative membrane protein. (143 aa)    
Predicted Functional Partners:
CBO0866
Putative membrane protein.
     
  0.900
CBO3588
Conserved hypothetical protein.
       0.634
CBO0871
Conserved hypothetical protein; Similar to The C-terminal regions of several regulators including Escherichia coli, and Escherichia coli O157:H7 regulatory protein nsr nsr or b2163 or z3420 or ecs3055 SWALL:NSR_ECOLI (SWALL:P33023) (219 aa) fasta scores: E(): 0.029, 28.44 38d in 116 aa, and to Bacillus cereus catabolite gene activator bc3449 SWALL:Q81AV5 (EMBL:AE017009) (230 aa) fasta scores: E(): 1.3e-09,34.95 38d in 123 aa.
 
     0.601
CBO3590
LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.587
CBO3591
Putative alkaline serine protease.
 
     0.559
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.524
pyrD
Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
    0.520
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
    0.505
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
    0.484
CBO1548
cNMP-binding regulatory protein.
 
     0.481
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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