STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO3590LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
CBO3589
Putative membrane protein.
       0.587
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.557
CBO3591
Putative alkaline serine protease.
  
  
 0.557
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.555
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.513
sigA
RNA polymerase sigma factor (sigma-43); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.500
CBO3588
Conserved hypothetical protein.
       0.486
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.462
selB
Selenocysteine-specific elongation factor.
 
   
 0.430
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.404
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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