Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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CBO3593Putative NAD-dependent 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)    
Predicted Functional Partners:
CBO3592
LysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.697
CBO3567
Putative metallo-beta-lactamase superfamily protein.
   
    0.596
metH
Putative methionine synthase.
   
  
 0.581
maf
Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
   0.562
thrC
Threonine synthase.
  
  
 0.551
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.477
birA
BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.461
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
       0.461
CBO0196
Putative kinase; Similar to Clostridium tetani uridine kinase ctc00344 SWALL:Q898U6 (EMBL:AE015937) (552 aa) fasta scores: E(): 6.7e-122, 61.05 38d in 552 aa, and to Clostridium acetobutylicum fision threonyl-trna synthetase cac0672 SWALL:Q97L90 (EMBL:AE007582) (553 aa) fasta scores: E(): 4.3e-123, 61.84 38d in 553 aa.
   
  0.458
udk
Uridine kinase.
   
  0.458
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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