Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO3606Putative exported peptidase. (311 aa)    
Predicted Functional Partners:
CBO0161
Putative secreted peptidase; Similar to Clostridium tetani conserved membrane-associated protein ctc00316 SWALL:Q898X1 (EMBL:AE015936) (271 aa) fasta scores: E(): 1.1e-27, 51.6 id in 250 aa, and to Clostridium perfringens hypothetical protein Cpe2182 cpe2182 SWALL:Q8XID9 (EMBL:AP003193) (256 aa) fasta scores: E(): 1.5e-17, 32.94 38d in 255 aa.
  
    0.759
lepB-2
Putative signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.642
fliY
Flagellar motor switch protein FliY.
   
   0.628
CBO3274
Putative transglycosylase, SLT family.
  
 0.587
CBO3083
Penicillin-binding protein.
  
  
 0.577
CBO3605
Putative 2-nitropropane dioxygenase.
       0.538
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
    0.527
CBO3604A
MarR-family transcriptional regulator.
  
    0.525
CBO3607
Putative DNA replication protein.
       0.518
dnaC
DNA replication protein.
       0.517
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (12%) [HD]