STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK77568.1Hypothetical protein. (247 aa)    
Predicted Functional Partners:
ABK78558.1
S-adenosylmethionine synthetase; COG0192.
  
  
 0.864
ABK77566.1
Methionine synthase I (cobalamin-dependent), methyltransferase domain; COG0646.
  
  
 0.860
ABK76905.1
Homoserine dehydrogenase; COG0460.
  
  
 0.753
ABK78013.1
S-adenosylhomocysteine hydrolase; COG0499; Belongs to the adenosylhomocysteinase family.
  
  
 0.646
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.632
folD
5,10-methylene-tetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
  
 0.625
ABK77569.1
NTP pyrophosphohydrolase; COG0494.
       0.604
ABK77224.1
Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
   
  
 0.519
ABK76762.1
Folate-dependent phosphoribosylglycinamide formyltransferase; COG0299.
     
 0.504
ABK78195.1
malate/L-lactate dehydrogenase; COG0039; Belongs to the LDH/MDH superfamily.
     
 0.501
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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