STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK77573.12-methylthioadenine synthetase; COG0621. (421 aa)    
Predicted Functional Partners:
ABK77574.1
Fumarate hydratase/fumarase; COG1027.
       0.819
rrp4
Exosome complex RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
  
 
 
 0.813
ABK77572.1
Cell division GTPase; COG0206.
 
     0.743
ABK78649.1
4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein; COG0476.
     
 0.654
ABK77597.1
ATPases involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.636
rrp41
RNase PH; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
 
   0.622
ABK77575.1
Phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.589
ABK76705.1
ATPase of the PP-loop superfamily; COG0037.
 
   
 0.567
ABK76657.1
Hydrolase of the metallo-beta-lactamase superfamily; COG0595.
 
   
 0.554
ABK76757.1
isoleucyl-tRNA synthetase; COG0060; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.550
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.