STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (311 aa)    
Predicted Functional Partners:
ABK77246.1
Isopropylmalate/homocitrate/citramalate synthase; COG0119; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.992
ilvD
Dihydroxyacid dehydratase/phosphogluconate dehydratase; COG0129; Belongs to the IlvD/Edd family.
  
 0.981
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.917
ABK78579.1
Aspartate/tyrosine/aromatic aminotransferase; COG0436.
  
 
 0.914
ilvE-2
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.908
ABK77476.1
Threonine dehydratase; COG1171.
  
 
 0.897
ABK76905.1
Homoserine dehydrogenase; COG0460.
  
 
 0.887
ABK78505.1
Homoserine kinase; COG0083.
  
 
 0.858
ABK77831.1
2-isopropylmalate synthase; COG0119.
 
 
 0.853
ABK77996.1
Hypothetical protein.
       0.752
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.