STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glyAGlycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (441 aa)    
Predicted Functional Partners:
ABK76762.1
Folate-dependent phosphoribosylglycinamide formyltransferase; COG0299.
  
 0.983
folD
5,10-methylene-tetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 0.980
ABK76689.1
Formyltetrahydrofolate deformylase; COG0788.
  
 
 0.960
ABK77003.1
Phosphoserine phosphatase; COG0560.
  
 0.953
ABK77614.1
8-amino-7-oxononanoate synthase; COG0156.
  
 
 0.949
ABK77476.1
Threonine dehydratase; COG1171.
    
 0.940
ABK77566.1
Methionine synthase I (cobalamin-dependent), methyltransferase domain; COG0646.
     
 0.940
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.940
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 
 0.937
ABK77699.1
Adenylosuccinate lyase; COG0015.
  
  
 0.925
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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