STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK78478.1Phosphoribosylpyrophosphate synthetase; COG0462; Belongs to the ribose-phosphate pyrophosphokinase family. (283 aa)    
Predicted Functional Partners:
purF
Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.951
ABK76684.1
Ribose 5-phosphate isomerase; COG0120.
  
 
 0.944
ABK76930.1
Phosphomannomutase; COG1109; Belongs to the phosphohexose mutase family.
 
 0.940
ABK76731.1
Transketolase, N-terminal subunit; COG0021.
    
  0.913
ABK76732.1
Transketolase, C-terminal subunit; COG0021.
    
  0.913
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.891
ABK78638.1
ATP phosphoribosyltransferase; COG0040.
  
 
 0.883
fusA
Translation elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 sub [...]
 
 
 0.826
eif5a
Translation elongation factor P (EF-P)/translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
    0.822
ABK76712.1
Pyridoxine/pyridoxal 5-phosphate biosynthesis enzyme; COG0214; Belongs to the PdxS/SNZ family.
   
 
  0.804
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.