STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisIphosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (108 aa)    
Predicted Functional Partners:
ABK78638.1
ATP phosphoribosyltransferase; COG0040.
 
 
 0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
  
 0.999
hisB
Imidazoleglycerol-phosphate dehydratase; COG0131.
  
 0.999
hisH
Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.999
hisA
Phosphoribosyl formimino-5-aminoimidazole isomerase; COG0106.
 
 0.999
ABK78645.1
Imidazoleglycerol-phosphate synthase, cyclase subunit; COG0107; Belongs to the HisA/HisF family.
  
 0.999
ABK78640.1
Histidinol-phosphate aminotransferase; COG0079.
 
  
 0.948
ABK78598.1
Threonine-phosphate decarboxylase; COG0079.
 
  
 0.844
ABK77003.1
Phosphoserine phosphatase; COG0560.
  
  
 0.836
ABK78641.1
Phosphatase; COG0546.
  
  
 0.752
Your Current Organism:
Cenarchaeum symbiosum
NCBI taxonomy Id: 414004
Other names: C. symbiosum A, Cenarchaeum symbiosum A
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