Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A182ISC9GGACT domain-containing protein. (159 aa)    
Predicted Functional Partners:
A0A182JCA4
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
     
  0.698
A0A182IQ72
Dihydrolipoyl dehydrogenase.
    
 0.646
A0A182J4F6
Uncharacterized protein.
    
 0.646
A0A182IWA5
Lipoyl-binding domain-containing protein.
     
  0.541
A0A182J8Z0
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
     
  0.541
A0A182JCK5
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
     
  0.541
A0A182JD95
Transket_pyr domain-containing protein.
     
  0.494
A0A182JDB8
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
  0.494
A0A182ITM5
Uncharacterized protein; Belongs to the phosphohexose mutase family.
  
 
  0.480
Your Current Organism:
Anopheles atroparvus
NCBI taxonomy Id: 41427
Other names: A. atroparvus
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