STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182IZ32Poly [ADP-ribose] polymerase. (864 aa)    
Predicted Functional Partners:
A0A182IX37
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.910
A0A182IWH9
Uncharacterized protein.
  
 
 0.905
A0A182ING1
Uncharacterized protein.
    
 0.831
A0A182J306
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.831
A0A182JD53
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.815
A0A182JC89
Uncharacterized protein.
    
 0.794
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.783
A0A182IPM5
RPA_C domain-containing protein.
   
 0.779
A0A182IX30
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.775
A0A182J128
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
    
 0.775
Your Current Organism:
Anopheles atroparvus
NCBI taxonomy Id: 41427
Other names: A. atroparvus
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