STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182J2F5TPR_REGION domain-containing protein. (455 aa)    
Predicted Functional Partners:
A0A182JIJ8
Histone acetyltransferase type B catalytic subunit.
   
 
 0.990
A0A182JJT9
WD_REPEATS_REGION domain-containing protein.
   
 
 0.970
A0A182IZV6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.957
A0A182JI78
Histone H3; Belongs to the histone H3 family.
   
 
 0.956
A0A182IZK0
Uncharacterized protein.
   
 
 0.925
A0A182IS57
Histone H2B; Belongs to the histone H2B family.
    
 
 0.725
A0A182JDX5
Histone H2B; Belongs to the histone H2B family.
    
 
 0.725
A0A182JD53
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.717
A0A182J7G2
Uncharacterized protein.
   
 
 0.664
A0A182J1P1
Histone H2A; Belongs to the histone H2A family.
    
 
 0.662
Your Current Organism:
Anopheles atroparvus
NCBI taxonomy Id: 41427
Other names: A. atroparvus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.