STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182JI09Uncharacterized protein. (436 aa)    
Predicted Functional Partners:
A0A182JI78
Histone H3; Belongs to the histone H3 family.
    
 0.856
A0A182IZK0
Uncharacterized protein.
    
 0.844
A0A182IZV6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.837
A0A182IY45
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
   
 0.755
A0A182JAB4
Amine oxidase.
   
 0.657
A0A182IS57
Histone H2B; Belongs to the histone H2B family.
    
  0.654
A0A182JDX5
Histone H2B; Belongs to the histone H2B family.
    
  0.654
A0A182J6T9
Histone H2A; Belongs to the histone H2A family.
    
 0.653
A0A182JAV6
Uncharacterized protein.
    
 0.653
A0A182JIT9
Histone H2A; Belongs to the histone H2A family.
    
 0.653
Your Current Organism:
Anopheles atroparvus
NCBI taxonomy Id: 41427
Other names: A. atroparvus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.