Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbx1Ring-box 1, E3 ubiquitin protein ligase. (108 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.999
cul2
Cullin 2; Belongs to the cullin family.
    
 0.999
ddb1
Damage-specific DNA binding protein 1.
    
 0.999
eloc
Elongin C paralog a; Belongs to the SKP1 family.
   
 0.999
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.999
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.999
CUL7
Cullin 7; Belongs to the cullin family.
    
 0.998
fbxw8
F-box and WD repeat domain containing 8.
    
 0.998
ercc8
Excision repair cross-complementation group 8.
    
 0.997
dtl
Denticleless E3 ubiquitin protein ligase homolog (Drosophila).
    
 0.997
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (26%) [HD]