close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111238220CRK proto-oncogene, adaptor protein. (315 aa)    
Predicted Functional Partners:
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.976
dock1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.972
abl2
Tyrosine-protein kinase.
    
 0.965
abl1
Tyrosine-protein kinase.
    
 0.965
LOC111227470
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.963
LOC111221651
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.963
rapgef1
Rap guanine nucleotide exchange factor (GEF) 1b.
    
 0.936
rhoq
Ras homolog family member Q.
   
 
 0.933
egfr
Receptor protein-tyrosine kinase.
    
 0.932
LOC111237405
Receptor protein-tyrosine kinase.
    
 0.932
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: medium (44%) [HD]