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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111224908Cyclin D2, b; Belongs to the cyclin family. (294 aa)    
Predicted Functional Partners:
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.981
rb1
Retinoblastoma 1.
    
 0.978
LOC111233740
Retinoblastoma-like 2 (p130).
    
 0.977
rbl1
Retinoblastoma-like 1 (p107).
    
 0.977
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.975
LOC111222103
Cyclin-dependent kinase inhibitor 1A.
   
 0.965
LOC111224780
Uncharacterized protein.
   
 0.965
LOC111236603
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
    
 0.961
cdkn2c
Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).
    
 0.957
LOC111217648
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
   
 0.953
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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