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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adam23ADAM metallopeptidase domain 23. (782 aa)    
Predicted Functional Partners:
lgi2
Leucine-rich repeat LGI family, member 2a.
     
 0.877
LOC111231457
Leucine-rich repeat LGI family, member 2b.
    
 0.757
lgi3
Leucine-rich repeat LGI family, member 3.
     
 0.746
nhlrc1
RING-type domain-containing protein.
      
 0.653
mlf1
Myeloid leukemia factor 1.
   
  
 0.562
kansl3
KAT8 regulatory NSL complex subunit 3.
      
 0.525
LOC111217546
Uncharacterized protein.
  
 
0.523
LOC111219972
ADAM metallopeptidase domain 11.
  
 
0.521
adam22
ADAM metallopeptidase domain 22.
    
0.513
LOC111235175
Leucine-rich, glioma inactivated 1a.
     
 0.499
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.