Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adam23ADAM metallopeptidase domain 23. (782 aa)    
Predicted Functional Partners:
lgi2
Leucine-rich repeat LGI family, member 2a.
     
 0.989
lgi3
Leucine-rich repeat LGI family, member 3.
     
 0.913
nhlrc1
RING-type domain-containing protein.
      
 0.860
LOC111231457
Leucine-rich repeat LGI family, member 2b.
   
 0.779
kansl3
KAT8 regulatory NSL complex subunit 3.
      
 0.715
mlf1
Myeloid leukemia factor 1.
      
 0.714
adam22
ADAM metallopeptidase domain 22.
   
 0.685
LOC111219972
ADAM metallopeptidase domain 11.
   
 0.685
LOC111217546
Uncharacterized protein.
   
 0.685
LOC111235175
Leucine-rich, glioma inactivated 1a.
     
 0.655
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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