Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111224722DEF6 guanine nucleotide exchange factor c. (634 aa)    
Predicted Functional Partners:
mst1r
Macrophage stimulating 1 receptor b.
   
  0.520
met
MET proto-oncogene, receptor tyrosine kinase.
   
  0.520
LOC111222844
Macrophage stimulating 1 receptor a.
   
  0.520
LOC111217986
RAS protein activator like 3.
   
 0.401
LOC111222592
Synaptic Ras GTPase activating protein 1b.
   
 0.401
dab2ip
DAB2 interacting protein b.
   
 0.401
LOC111223115
Uncharacterized protein.
   
 0.401
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
 0.401
rasal2
RAS protein activator like 2.
   
 0.401
LOC111237461
Uncharacterized protein.
   
 0.401
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.