close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111224722DEF6 guanine nucleotide exchange factor c. (634 aa)    
Predicted Functional Partners:
mst1r
Macrophage stimulating 1 receptor b.
   
 0.627
met
MET proto-oncogene, receptor tyrosine kinase.
   
 0.627
LOC111222844
Macrophage stimulating 1 receptor a.
   
 0.627
LOC111217986
RAS protein activator like 3.
    
 0.471
LOC111222592
Synaptic Ras GTPase activating protein 1b.
    
 0.471
dab2ip
DAB2 interacting protein b.
    
 0.471
LOC111223115
Uncharacterized protein.
    
 0.471
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.471
rasal2
RAS protein activator like 2.
    
 0.471
LOC111237461
Uncharacterized protein.
    
 0.471
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.