LOC111220546 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC111220546

Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (540 aa)

Predicted Functional Partners:

LOC111230812

0.900

galc

0.851

LOC111227730

0.797

gla

0.797

LOC111239406

0.797

arsa

0.794

gm2a

0.750

ppt1

0.735

tmem130

0.734

gba

0.734

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111220546	LOC111227730	ENSSDUP00000001351	ENSSDUP00000006684	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Alpha-galactosidase.	0.797
LOC111220546	LOC111230812	ENSSDUP00000001351	ENSSDUP00000027513	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Surfactant protein Bb.	0.900
LOC111220546	LOC111239406	ENSSDUP00000001351	ENSSDUP00000016055	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Alpha-galactosidase.	0.797
LOC111220546	arsa	ENSSDUP00000001351	ENSSDUP00000020589	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Arylsulfatase A.	0.794
LOC111220546	galc	ENSSDUP00000001351	ENSSDUP00000030146	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Galactosylceramidase b.	0.851
LOC111220546	gba	ENSSDUP00000001351	ENSSDUP00000008845	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Glucosylceramidase.	0.734
LOC111220546	gla	ENSSDUP00000001351	ENSSDUP00000006788	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Alpha-galactosidase.	0.797
LOC111220546	gm2a	ENSSDUP00000001351	ENSSDUP00000019737	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	GM2 ganglioside activator.	0.750
LOC111220546	ppt1	ENSSDUP00000001351	ENSSDUP00000029111	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).	0.735
LOC111220546	tmem130	ENSSDUP00000001351	ENSSDUP00000007307	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	Transmembrane protein 130.	0.734
LOC111227730	LOC111220546	ENSSDUP00000006684	ENSSDUP00000001351	Alpha-galactosidase.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.797
LOC111227730	LOC111230812	ENSSDUP00000006684	ENSSDUP00000027513	Alpha-galactosidase.	Surfactant protein Bb.	0.797
LOC111227730	LOC111239406	ENSSDUP00000006684	ENSSDUP00000016055	Alpha-galactosidase.	Alpha-galactosidase.	0.901
LOC111230812	LOC111220546	ENSSDUP00000027513	ENSSDUP00000001351	Surfactant protein Bb.	Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.	0.900
LOC111230812	LOC111227730	ENSSDUP00000027513	ENSSDUP00000006684	Surfactant protein Bb.	Alpha-galactosidase.	0.797
LOC111230812	LOC111239406	ENSSDUP00000027513	ENSSDUP00000016055	Surfactant protein Bb.	Alpha-galactosidase.	0.797
LOC111230812	arsa	ENSSDUP00000027513	ENSSDUP00000020589	Surfactant protein Bb.	Arylsulfatase A.	0.794
LOC111230812	galc	ENSSDUP00000027513	ENSSDUP00000030146	Surfactant protein Bb.	Galactosylceramidase b.	0.851
LOC111230812	gba	ENSSDUP00000027513	ENSSDUP00000008845	Surfactant protein Bb.	Glucosylceramidase.	0.734
LOC111230812	gla	ENSSDUP00000027513	ENSSDUP00000006788	Surfactant protein Bb.	Alpha-galactosidase.	0.797

page 1 of 3

Server load: low (20%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About