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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (724 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.805
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.755
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
 0.695
LOC111234739
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
    
 0.695
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.671
pik3cb
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.671
LOC111236831
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
 0.661
LOC111228886
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.
    
 0.661
LOC111233334
PH domain-containing protein.
    
 0.661
pik3ca
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.661
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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