LOC111223500 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC111223500

Growth factor receptor-bound protein 10a. (555 aa)

Predicted Functional Partners:

ret

0.573

grb2

0.572

LOC111237924

0.570

LOC111217738

0.570

LOC111231251

0.570

LOC111228731

0.570

wdr90

0.520

LOC111235891

0.512

LOC111230241

0.512

LOC111216690

0.512

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111216690	LOC111223500	ENSSDUP00000023211	ENSSDUP00000001608	GRB2 related adaptor protein b.	Growth factor receptor-bound protein 10a.	0.512
LOC111216690	grb2	ENSSDUP00000023211	ENSSDUP00000024464	GRB2 related adaptor protein b.	Growth factor receptor-bound protein 2b.	0.430
LOC111217738	LOC111223500	ENSSDUP00000010846	ENSSDUP00000001608	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10a.	0.570
LOC111217738	grb2	ENSSDUP00000010846	ENSSDUP00000024464	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 2b.	0.582
LOC111223500	LOC111216690	ENSSDUP00000001608	ENSSDUP00000023211	Growth factor receptor-bound protein 10a.	GRB2 related adaptor protein b.	0.512
LOC111223500	LOC111217738	ENSSDUP00000001608	ENSSDUP00000010846	Growth factor receptor-bound protein 10a.	Tyrosine-protein kinase receptor.	0.570
LOC111223500	LOC111228731	ENSSDUP00000001608	ENSSDUP00000016741	Growth factor receptor-bound protein 10a.	Tyrosine-protein kinase receptor.	0.570
LOC111223500	LOC111230241	ENSSDUP00000001608	ENSSDUP00000021605	Growth factor receptor-bound protein 10a.	GRB2 related adaptor protein a.	0.512
LOC111223500	LOC111231251	ENSSDUP00000001608	ENSSDUP00000016457	Growth factor receptor-bound protein 10a.	Tyrosine-protein kinase receptor.	0.570
LOC111223500	LOC111235891	ENSSDUP00000001608	ENSSDUP00000016754	Growth factor receptor-bound protein 10a.	GRB2 related adaptor protein 2b.	0.512
LOC111223500	LOC111237924	ENSSDUP00000001608	ENSSDUP00000002119	Growth factor receptor-bound protein 10a.	Tyrosine-protein kinase receptor.	0.570
LOC111223500	grb2	ENSSDUP00000001608	ENSSDUP00000024464	Growth factor receptor-bound protein 10a.	Growth factor receptor-bound protein 2b.	0.572
LOC111223500	ret	ENSSDUP00000001608	ENSSDUP00000025257	Growth factor receptor-bound protein 10a.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.573
LOC111223500	wdr90	ENSSDUP00000001608	ENSSDUP00000002570	Growth factor receptor-bound protein 10a.	WD repeat domain 90.	0.520
LOC111228731	LOC111223500	ENSSDUP00000016741	ENSSDUP00000001608	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10a.	0.570
LOC111228731	LOC111231251	ENSSDUP00000016741	ENSSDUP00000016457	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.902
LOC111228731	grb2	ENSSDUP00000016741	ENSSDUP00000024464	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 2b.	0.956
LOC111230241	LOC111223500	ENSSDUP00000021605	ENSSDUP00000001608	GRB2 related adaptor protein a.	Growth factor receptor-bound protein 10a.	0.512
LOC111230241	grb2	ENSSDUP00000021605	ENSSDUP00000024464	GRB2 related adaptor protein a.	Growth factor receptor-bound protein 2b.	0.431
LOC111231251	LOC111223500	ENSSDUP00000016457	ENSSDUP00000001608	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10a.	0.570