LOC111219852 protein (Seriola dumerili) - STRING interaction network

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[Homology]

Score

LOC111219852

STIP1 homology and U-Box containing protein 1. (284 aa)

Predicted Functional Partners:

cftr

0.982

LOC111233015

0.981

ube2w

0.976

bag3

0.974

LOC111234299

0.971

bag2

0.967

hspa4

0.956

LOC111234347

0.956

prkn

0.955

hspbp1

0.946

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111219852	LOC111233015	ENSSDUP00000001633	ENSSDUP00000028226	STIP1 homology and U-Box containing protein 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.981
LOC111219852	LOC111234299	ENSSDUP00000001633	ENSSDUP00000028242	STIP1 homology and U-Box containing protein 1.	Interferon regulatory factor.	0.971
LOC111219852	LOC111234347	ENSSDUP00000001633	ENSSDUP00000026825	STIP1 homology and U-Box containing protein 1.	Heat shock protein 4a.	0.956
LOC111219852	bag2	ENSSDUP00000001633	ENSSDUP00000032710	STIP1 homology and U-Box containing protein 1.	BCL2 associated athanogene 2.	0.967
LOC111219852	bag3	ENSSDUP00000001633	ENSSDUP00000024862	STIP1 homology and U-Box containing protein 1.	BCL2 associated athanogene 3.	0.974
LOC111219852	cftr	ENSSDUP00000001633	ENSSDUP00000022533	STIP1 homology and U-Box containing protein 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.982
LOC111219852	hspa4	ENSSDUP00000001633	ENSSDUP00000008313	STIP1 homology and U-Box containing protein 1.	Heat shock protein 4b.	0.956
LOC111219852	hspbp1	ENSSDUP00000001633	ENSSDUP00000023327	STIP1 homology and U-Box containing protein 1.	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1.	0.946
LOC111219852	prkn	ENSSDUP00000001633	ENSSDUP00000018140	STIP1 homology and U-Box containing protein 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.955
LOC111219852	ube2w	ENSSDUP00000001633	ENSSDUP00000017131	STIP1 homology and U-Box containing protein 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.976
LOC111233015	LOC111219852	ENSSDUP00000028226	ENSSDUP00000001633	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	STIP1 homology and U-Box containing protein 1.	0.981
LOC111233015	LOC111234299	ENSSDUP00000028226	ENSSDUP00000028242	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Interferon regulatory factor.	0.410
LOC111233015	LOC111234347	ENSSDUP00000028226	ENSSDUP00000026825	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Heat shock protein 4a.	0.933
LOC111233015	bag2	ENSSDUP00000028226	ENSSDUP00000032710	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BCL2 associated athanogene 2.	0.945
LOC111233015	bag3	ENSSDUP00000028226	ENSSDUP00000024862	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BCL2 associated athanogene 3.	0.577
LOC111233015	hspa4	ENSSDUP00000028226	ENSSDUP00000008313	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Heat shock protein 4b.	0.933
LOC111233015	prkn	ENSSDUP00000028226	ENSSDUP00000018140	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.676
LOC111234299	LOC111219852	ENSSDUP00000028242	ENSSDUP00000001633	Interferon regulatory factor.	STIP1 homology and U-Box containing protein 1.	0.971
LOC111234299	LOC111233015	ENSSDUP00000028242	ENSSDUP00000028226	Interferon regulatory factor.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.410
LOC111234347	LOC111219852	ENSSDUP00000026825	ENSSDUP00000001633	Heat shock protein 4a.	STIP1 homology and U-Box containing protein 1.	0.956