Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
txnl1Thioredoxin-like 1. (289 aa)    
Predicted Functional Partners:
psmd14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.969
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
   0.938
psmd7
Proteasome 26S subunit, non-ATPase 7.
   
 
 0.938
psmb2
Proteasome subunit beta.
   
   0.922
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
   0.890
psmd12
Proteasome 26S subunit, non-ATPase 12.
   
 
 0.890
psmb4
Proteasome subunit beta; Belongs to the peptidase T1B family.
   
   0.876
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.875
psmc1
Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.
   
 
 0.871
psmc6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
   0.868
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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