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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ostf1Osteoclast stimulating factor 1. (214 aa)    
Predicted Functional Partners:
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.592
ccnc
Cyclin C; Belongs to the cyclin family.
     
 0.542
cdc5l
CDC5 cell division cycle 5-like (S. pombe).
    
 
 0.495
actr8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.488
ppp1r14b
Protein phosphatase 1, regulatory (inhibitor) subunit 14Bb.
    
 0.479
pdcd5
Programmed cell death 5.
    
 
 0.439
LOC111234464
Spermidine/spermine N1-acetyltransferase family member 2b.
    
 
 0.437
gak
Cyclin G associated kinase.
    
 0.435
rnf141
Ring finger protein 141.
      
 0.431
ubxn7
UBX domain protein 7.
    
 0.417
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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