rer1 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rer1

Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (187 aa)

Predicted Functional Partners:

tmed2

0.863

LOC111217911

0.810

canx

0.810

ddost

0.759

atp5po

0.751

pex10

0.732

COPB2

0.711

LOC111229005

0.711

ergic3

0.693

KDELR2

0.692

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPB2	KDELR2	ENSSDUP00000013857	ENSSDUP00000013780	WD_REPEATS_REGION domain-containing protein.	ER lumen protein-retaining receptor.	0.607
COPB2	LOC111229005	ENSSDUP00000013857	ENSSDUP00000018898	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.544
COPB2	ddost	ENSSDUP00000013857	ENSSDUP00000004373	WD_REPEATS_REGION domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.603
COPB2	ergic3	ENSSDUP00000013857	ENSSDUP00000003019	WD_REPEATS_REGION domain-containing protein.	ERGIC and golgi 3.	0.485
COPB2	rer1	ENSSDUP00000013857	ENSSDUP00000001940	WD_REPEATS_REGION domain-containing protein.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.711
COPB2	tmed2	ENSSDUP00000013857	ENSSDUP00000032797	WD_REPEATS_REGION domain-containing protein.	Transmembrane p24 trafficking protein 2.	0.684
KDELR2	COPB2	ENSSDUP00000013780	ENSSDUP00000013857	ER lumen protein-retaining receptor.	WD_REPEATS_REGION domain-containing protein.	0.607
KDELR2	LOC111229005	ENSSDUP00000013780	ENSSDUP00000018898	ER lumen protein-retaining receptor.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.607
KDELR2	rer1	ENSSDUP00000013780	ENSSDUP00000001940	ER lumen protein-retaining receptor.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.692
KDELR2	tmed2	ENSSDUP00000013780	ENSSDUP00000032797	ER lumen protein-retaining receptor.	Transmembrane p24 trafficking protein 2.	0.786
LOC111217911	ddost	ENSSDUP00000003096	ENSSDUP00000004373	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.812
LOC111217911	ergic3	ENSSDUP00000003096	ENSSDUP00000003019	Uncharacterized protein.	ERGIC and golgi 3.	0.401
LOC111217911	rer1	ENSSDUP00000003096	ENSSDUP00000001940	Uncharacterized protein.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.810
LOC111229005	COPB2	ENSSDUP00000018898	ENSSDUP00000013857	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	WD_REPEATS_REGION domain-containing protein.	0.544
LOC111229005	KDELR2	ENSSDUP00000018898	ENSSDUP00000013780	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	ER lumen protein-retaining receptor.	0.607
LOC111229005	ddost	ENSSDUP00000018898	ENSSDUP00000004373	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.603
LOC111229005	ergic3	ENSSDUP00000018898	ENSSDUP00000003019	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	ERGIC and golgi 3.	0.485
LOC111229005	rer1	ENSSDUP00000018898	ENSSDUP00000001940	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.711
LOC111229005	tmed2	ENSSDUP00000018898	ENSSDUP00000032797	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Transmembrane p24 trafficking protein 2.	0.684
atp5po	rer1	ENSSDUP00000007103	ENSSDUP00000001940	ATP synthase peripheral stalk subunit OSCP.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.751