Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptpn1Tyrosine-protein phosphatase non-receptor type. (437 aa)    
Predicted Functional Partners:
LOC111237924
Tyrosine-protein kinase receptor.
    
 0.975
LOC111231251
Tyrosine-protein kinase receptor.
    
 0.975
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.939
LOC111222989
Uncharacterized protein.
    
 0.931
irs2
Insulin receptor substrate 2b.
    
 0.926
LOC111222710
Insulin receptor substrate 2a.
    
 0.926
LOC111233462
Insulin receptor substrate 4a.
    
 0.926
LOC111233019
Si:ch73-335l21.1.
    
 0.926
LOC111217738
Tyrosine-protein kinase receptor.
    
 0.763
LOC111228731
Tyrosine-protein kinase receptor.
    
 0.763
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (14%) [HD]