Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kpna6Importin subunit alpha; Belongs to the importin alpha family. (547 aa)    
Predicted Functional Partners:
kpnb1
Karyopherin (importin) beta 1.
   
 0.937
nup50
Nucleoporin 50.
   
 
 0.727
cse1l
CSE1 chromosome segregation 1-like (yeast).
   
 
 0.699
rcc1
Regulator of chromosome condensation 1.
   
 
 0.676
rnmt
mRNA cap guanine-N7 methyltransferase.
   
   0.670
ipo5
Karyopherin (importin) beta 3.
   
 
 0.658
LOC111218510
RAN binding protein 2.
   
 
 0.657
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 
 0.643
yars1
Tyrosine--tRNA ligase.
   
  
 0.630
nup98
Nucleoporin 98.
   
 
 0.630
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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