STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111233164Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)    
Predicted Functional Partners:
rb1
Retinoblastoma 1.
   
 0.977
LOC111231549
Recombination signal binding protein for immunoglobulin kappa J region a.
   
 0.954
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
   
 0.954
ENSSDUP00000000441
AT rich interactive domain 4A (RBP1-like).
   
 0.947
arid4b
Translocase of outer mitochondrial membrane 20.
   
 0.947
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.947
ctbp1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.906
LOC111226453
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.906
LOC111235306
Uncharacterized protein.
    
 0.906
LOC111228389
TLE family member 3, transcriptional corepressor.
    
 0.901
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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