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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111233182Transcription factor SOX. (371 aa)    
Predicted Functional Partners:
tcf7
Transcription factor 7.
    
 0.508
lef1
Lymphoid enhancer-binding factor 1.
    
 0.505
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.501
LOC111224272
HMG box domain-containing protein.
  
 
0.451
LOC111229402
Junction plakoglobin a.
    
 0.449
LOC111222989
Uncharacterized protein.
    
 0.449
LOC111236265
Uncharacterized protein.
    
 0.449
LOC111229733
HMG box domain-containing protein.
    
0.424
LOC111236575
SRY-box transcription factor 6.
    
0.424
ENSSDUP00000008954
POU domain, class 5, transcription factor 3.
    
 0.419
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.