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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dkk2Dickkopf WNT signaling pathway inhibitor 2. (246 aa)    
Predicted Functional Partners:
lrp6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.958
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.958
LOC111233140
Dickkopf_N domain-containing protein.
  
  
 
0.902
kremen1
Kringle containing transmembrane protein 1.
    
 0.756
bmp4
Bone morphogenetic protein 4.
    
 
 0.598
LOC111220642
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.598
dkk1
Dickkopf WNT signaling pathway inhibitor 1a.
     
0.575
LOC111228615
Protein inhibitor of activated STAT, 1b.
   
 
 0.469
wwox
WW domain containing oxidoreductase.
    
 
 0.464
c6
Complement component 6.
   
  0.457
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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