STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC111220419Histone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
LOC111236427
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
   
 0.828
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.772
LOC111222703
Lysine (K)-specific demethylase 6A, like.
   
 0.759
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.759
ENSSDUP00000021538
Lysine (K)-specific demethylase 6B, b.
   
 0.759
kdm6b
Lysine (K)-specific demethylase 6B, a.
   
 0.759
ENSSDUP00000000054
Histone H2B; Belongs to the histone H2B family.
 
 
 0.735
setd2
SET domain containing 2, histone lysine methyltransferase.
    
 0.734
LOC111221389
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.727
ENSSDUP00000017647
Histone H2B; Belongs to the histone H2B family.
 
 
 0.718
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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