ENSSDUP00000003461 protein (Seriola dumerili)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSSDUP00000003461

Protein kinase domain-containing protein. (594 aa)

Predicted Functional Partners:

LOC111233015

0.644

DCAF7

0.587

LOC111220197

0.587

pin1

0.547

sumo1

0.532

cbfb

0.506

mecp2

0.497

atm

0.463

tp53inp1

0.456

ube2i

0.439

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF7	ENSSDUP00000003461	ENSSDUP00000030781	ENSSDUP00000003461	DDB1 and CUL4 associated factor 7.	Protein kinase domain-containing protein.	0.587
ENSSDUP00000003461	DCAF7	ENSSDUP00000003461	ENSSDUP00000030781	Protein kinase domain-containing protein.	DDB1 and CUL4 associated factor 7.	0.587
ENSSDUP00000003461	LOC111220197	ENSSDUP00000003461	ENSSDUP00000031842	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.587
ENSSDUP00000003461	LOC111233015	ENSSDUP00000003461	ENSSDUP00000028226	Protein kinase domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.644
ENSSDUP00000003461	atm	ENSSDUP00000003461	ENSSDUP00000015925	Protein kinase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.463
ENSSDUP00000003461	cbfb	ENSSDUP00000003461	ENSSDUP00000029961	Protein kinase domain-containing protein.	Core-binding factor subunit beta.	0.506
ENSSDUP00000003461	mecp2	ENSSDUP00000003461	ENSSDUP00000027357	Protein kinase domain-containing protein.	Methyl CpG binding protein 2.	0.497
ENSSDUP00000003461	pin1	ENSSDUP00000003461	ENSSDUP00000021085	Protein kinase domain-containing protein.	Peptidyl-prolyl cis-trans isomerase.	0.547
ENSSDUP00000003461	sumo1	ENSSDUP00000003461	ENSSDUP00000010585	Protein kinase domain-containing protein.	Small ubiquitin-related modifier.	0.532
ENSSDUP00000003461	tp53inp1	ENSSDUP00000003461	ENSSDUP00000020369	Protein kinase domain-containing protein.	Tumor protein p53 inducible nuclear protein 1.	0.456
ENSSDUP00000003461	ube2i	ENSSDUP00000003461	ENSSDUP00000003247	Protein kinase domain-containing protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.439
LOC111220197	ENSSDUP00000003461	ENSSDUP00000031842	ENSSDUP00000003461	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.587
LOC111233015	ENSSDUP00000003461	ENSSDUP00000028226	ENSSDUP00000003461	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Protein kinase domain-containing protein.	0.644
LOC111233015	atm	ENSSDUP00000028226	ENSSDUP00000015925	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Non-specific serine/threonine protein kinase.	0.998
LOC111233015	pin1	ENSSDUP00000028226	ENSSDUP00000021085	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Peptidyl-prolyl cis-trans isomerase.	0.834
LOC111233015	sumo1	ENSSDUP00000028226	ENSSDUP00000010585	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Small ubiquitin-related modifier.	0.859
LOC111233015	tp53inp1	ENSSDUP00000028226	ENSSDUP00000020369	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Tumor protein p53 inducible nuclear protein 1.	0.771
LOC111233015	ube2i	ENSSDUP00000028226	ENSSDUP00000003247	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.857
atm	ENSSDUP00000003461	ENSSDUP00000015925	ENSSDUP00000003461	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.463
atm	LOC111233015	ENSSDUP00000015925	ENSSDUP00000028226	Non-specific serine/threonine protein kinase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.998