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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111221140Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family. (1247 aa)    
Predicted Functional Partners:
LOC111238329
Tight junction protein 1a; Belongs to the MAGUK family.
    
0.959
LOC111234411
F11 receptor, tandem duplicate 1.
   
 0.955
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.924
LOC111237647
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.785
yap1
Yes-associated protein 1.
   
 0.752
afdn
Afadin, adherens junction formation factor a.
   
 
 0.692
LOC111229539
Tight junction protein 1b; Belongs to the MAGUK family.
    
 
0.614
LOC111229012
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 
 0.608
LOC111232024
Tight junction protein 3; Belongs to the MAGUK family.
  
   
0.561
LOC111223136
Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.535
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.