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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111221243IRF tryptophan pentad repeat domain-containing protein. (263 aa)    
Predicted Functional Partners:
mdm2
MDM2 proto-oncogene.
    
  0.912
LOC111234299
Interferon regulatory factor.
  
  
 
0.908
ENSSDUP00000023642
MYD88 innate immune signal transduction adaptor.
   
 0.537
LOC111220968
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.537
stat1
Signal transducer and activator of transcription.
   
 0.533
LOC111238387
Spi-1 proto-oncogene b.
   
 
 0.527
STUB1
STIP1 homology and U-box containing protein 1.
    
 
 0.500
LOC111219852
STIP1 homology and U-Box containing protein 1.
    
 
 0.500
LOC111219918
E1A binding protein p300 a.
    
 0.490
LOC111229253
CREB binding protein a.
    
 0.490
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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