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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSDUP00000003538PDZ domain-containing protein. (165 aa)    
Predicted Functional Partners:
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
 0.691
ift57
Intraflagellar transport 57 homolog (Chlamydomonas).
    
 0.599
ift80
Intraflagellar transport 80 homolog (Chlamydomonas).
    
 0.593
traf3ip1
TNF receptor-associated factor 3 interacting protein 1.
    
 0.587
ift172
Intraflagellar transport 172.
    
 0.583
ift88
Intraflagellar transport 88 homolog.
    
 0.553
ift81
Intraflagellar transport 81 homolog.
    
 0.533
ift52
Intraflagellar transport 52 homolog (Chlamydomonas).
    
 0.528
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.520
CASK-2
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.520
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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